The United Nations Office on Drugs and Crime reported that heroin traffickers in Central Asia made a profit of up to $1.4 Billion from the drug. The majority of the drug traffickers were based in Tajikistan, where they are able to handle the supply of the heroin from Afghanistan.70 to 75 percent of the illicit drug is smuggled by road, which leaves many in the surrounding area addicted to heroin.
The drug traffickers market up the price of the heroin by up to 600 percent when it arrives in its final destination of Russia.
Source: David Trilling, “Central Asia Key to Afghanistan Heroin Smuggling – UNODC,” Eurasiannet, Inside the Cocoon, May 18, 2012.

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